Course Details

This reading course explores the concept of behavioral epigenetics, particularly focusing on the impact of early maternal care on gene expression and brain development. Groundbreaking studies by Michael Meaney and colleagues revealed that variations in maternal care can significantly alter patterns of gene expression in brain regions related to stress response and social engagement, such as the hippocampus, prefrontal cortex, and amygdala. These changes influence behavioral traits, with well-cared-for animals exhibiting more social and exploratory behaviors. The research extends to humans, showing how early life experiences shape the development of trust, social engagement, and emotional resilience through epigenetic mechanisms. The text also discusses potential therapeutic interventions that could reverse the adverse effects of poor early care by altering gene expression patterns, emphasizing the importance of nurturing caregiving in promoting mental health.

  • Understand the concept of behavioral epigenetics and its significance in neuroscience.

  • Explain the impact of early maternal care on gene expression in the brain.

  • Identify the brain regions involved in the stress response and social engagement.

  • Describe the role of the amygdala in processing social stimuli and threats.

  • Discuss the implications of epigenetic research for therapeutic interventions in mental health.

  • Recognize the importance of nurturing caregiving in shaping emotional resilience and social behavior.

Course curriculum

    1. BEHAVIORAL EPIGENETICS AND ATTACHMENT – Jonathan Baylin

    2. Behavioral Epigenetics Quiz

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